1R6H, 1V3A, 2MBC1115619245ENSG00000184489ENSG00000275575ENSMUSG00000059895O75365Q9D658NM_007079NM_032611NM_001166388NM_001166389NM_001166390NM_008975NM_001357591NP_009010NP_116000NP_001159860NP_001159861NP_001159862NP_033001NP_001344520Protein tyrosine phosphatase type IVA 3 is an enzyme that in humans is encoded by the PTP4A3 gene.
[5] The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs).
PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes.
This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif.
Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane.