2OC3, 4GFU, 4GFV, 4NND2646919253ENSG00000072135ENSMUSG00000026126Q99952Q61152NM_001142370NM_014369NM_011206NP_001135842NP_055184NP_035336Tyrosine-protein phosphatase non-receptor type 18 is an enzyme that in humans is encoded by the PTPN18 gene.
PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-life.
This gene was found to be expressed in brain, colon tissues, and several different tumor-derived cell lines.
The biological function of this PTP has not yet been determined.