Puerto Rico is scheduled to compete at the 2023 Pan American Games in Santiago, Chile from October 20 to November 5, 2023.

Archer Jean Pizarro and judoka María Pérez were the country's flagbearers during the opening ceremony.

Puerto Rico qualified three fencers (two men and one woman) through the 2022 Pan American Fencing Championships in Asunción, Paraguay.

[17][18][19][20][21][22][23][24] Puerto Rico qualified a women's team (of 18 athletes) by virtue of its campaign in the 2022 Pan American Championships.

Puerto Rico qualified a female sport climber by virtue of the IFSC world rankings.

[27] Men Women Mixed Puerto Rico qualified a team of two triathletes (one man and one woman): Janarold Martínez and Zoe Adam.

Puerto Rico qualified a men's team (of 12 athletes) by reaching the final of the 2023 Central American and Caribbean Games.