The Virgin Islands team consisted of 12 athletes competing in six sports.

[1] Swimmers Adriel Sanes and Natalia Kuipers were the country's flagbearers during the opening ceremony.

[2] Meanwhile, archer Nicholas D'Amour and track athlete Michelle Smith were the country's flagbearers during the closing ceremony.

[1] The Virgin Islands qualified two archers during the 2022 Pan American Archery Championships.

The Virgin Islands qualified two male fencers through the 2022 Pan American Fencing Championships in Asunción, Paraguay.